TissueGUARD
TissueGUARD
  • Home
  • Products
  • Science
  • About Us
  • Contact
  • More
    • Home
    • Products
    • Science
    • About Us
    • Contact

  • Home
  • Products
  • Science
  • About Us
  • Contact

Advanced Polymer Solutions for Innovative Medical Technology

From Science to Solutions – Advanced Polymers for Real-World Impact

The TissueGUARD team combines deep expertise in polymer science with practical innovation to deliver advanced solutions for polymer-based devices. Whether for medical, industrial, or research applications, we support our partners with tailored materials, smart design, and precision-engineered components. Backed by decades of research, we bring high-performance polymer technologies from the lab to real-world use.


We provide

  •  Polymer material selection and formulation – including customized hydrogels tailored to your project 
  • Device design and engineering – from concept development to final product release 
  • Precision component development – including creation and manufacturing support 
  • Regulatory and QMS support – to guide your project through compliance and certification
     

 We design and support the production of polymeric devices that power the next generation of medical technology. 

Advanced Solutions for Organoid and Tissue Engineering

NO trypsin, NO collagenase, NO cell dissociation buffers

 Our proprietary biotechnology platform allows any living cells, tissue, or organoids to be cultured and collected from hydrogel materials without physically or chemically damaging the biological sample. 


We provide

  • Synthetic multi-component, fully defined hydrogel materials and devices to meet the needs of your cells
  • Customized hydrogel composition to preserve  pluripotency or direct morphogenesis   
  • Implemented biotechnology to collect the formed organoids or tissue for downstream application
  • Established QMS and pharma-grade chemicals to support your ATMP compliance
     

 We develop and manufacture bioinspired materials and devices suitable for isolating tissues or organoids without any attached foreign material (scaffold-free) to create a new approach for ex vivo engineered tissue, organoids, and cell production as therapeutics.   

Our Biotechnology 2D Platform

The material is designed to be stable during cell culturing and is provided as a coating in standard cell plates and intended for cells or flat tissue applications. The user can degrade the coating by simply adding a TAG enzyme at any point for collection or passaging of the cells or formed tissue. 


  • The Hydrogel coating is fully defined, Xeno-free, and tunable to maintain the cell characteristics.
  • Upon degradation of the cell culture carrier, any surface proteins, cell-cell, and cell-matrix contacts, as well as the extracellular matrix of the formed tissue, remain chemically and physically untouched. This significantly increases the survival rate of the cells and tissue to be further manipulated or implanted. 
  • The hydrogel coating is degraded to small, water-soluble molecules and can be removed by simple washing, providing a free-floating, ex vivo produced tissue without any artificial scaffold. 


Sample Applications: 

Corneal Lamellae transplantation (Descemet membrane endothelial keratoplasty DMEK)

 Bioengineered Retina transplantation 

Our Biotechnology 3D Platform

The material is designed to be cell responsive, allowing cell expansion and remodeling in three dimensions, and is intended for cells, organoids, and tissue applications. The user can degrade the scaffold by simply adding a TAG enzyme at any point for collection or passaging of the cells, organoids, or formed tissue.  


  • The Hydrogel composition is customizable for specific applications to direct the cell fate in the required linkage.
  • It can be used for the transportation and transferring of cells, organoids, or tissues. 
  • Upon degradation of the cell culture carrier, any cell-cell and cell-matrix contacts and the extracellular matrix of the formed tissue remains chemically and physically untouched.
  • The hydrogel is degraded to small, water-soluble molecules and can be removed by simple washing, providing a free-floating, ex vivo produced tissue without any artificial scaffold. 


Sample Applications: 

Capillary network (Angiogenesis) 

Mammary gland organoid (mammary epithelial morphogenesis)

Next-Generation of Cell Therapies

 For many diseases, tissue and organ transplantation provides the first-line and frequently the only life-saving therapeutic option. However, less than 15% of the global need for tissues and organs is met. For a number of these diseases, only a small portion of the organ needs to be regenerated to restore its function. Over the last decade, cell therapies as regenerative medicine were considered to be the most promising solution to overcome the donor shortage. Nevertheless, despite more than 4000 clinical studies, single-cell therapies remain ineffective overall. Cell therapies of "solid tissues" are facing three main issues:

  1. Maintaining cell morphogenesis.  
  2. Cell viability during and after implantation.
  3. Cell migration away from the target area. 


At TissueGUARD, we developed a few solutions which can overcome the above issues. These technologies increase cell viability and prevent their migration from the injected area, thus enabling the therapeutic outcome. 

Contact us for more details. 


Sample Applications: 

Neovascularization, Ischemic diseases, Neurodegenerative diseases

Copyright © 2019-2025 TissueGUARD - All Rights Reserved.

 

Powered by

This website uses cookies.

We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.

DeclineAccept