Advanced Solutions for Tissue Engineering

 Our biotechnology platform allows any live cells, tissue, or organs, to be encapsulated, manipulated, and released from our novel hydrogel materials without physically or chemically damaging the biological sample. We develop selectively enzymatically degradable bioinspired materials suitable for the isolation of tissues or organs without any attached foreign material (scaffold-free) in order to create a new approach for ex vivo tissue production. Additionally, the biological sample is produced and isolated under sterile conditions which tackles infection problems originating from non-sterile whole-size donor samples. 

The material is designed in a way that upon degradation of the cell culture carrier, any cell-cell and cell-matrix contacts as well as the extracellular matrix of the formed tissue remains chemically and physically untouched. The user has full control over the time point of degradation (e.g. cells reach confluence) with the addition of a selective enzyme at a low concentration. The culture carrier itself is degraded to small, water-soluble molecules, which enables to receive a free-floating, artificially produced tissue without the necessity of any carrier material.